經歷

• 高雄醫學大學 醫學系微生物暨免疫學科 助理教授 (現職)
• 國立台灣大學 醫學檢驗暨生物技術學系  研究學者 
• 國立台灣大學 醫學檢驗暨生物技術學系  博士後研究員 

參與課程

• 微生物免疫學相關課程之教學

學術著作 (2015-2025)

• 1.     Tai-Fen Lee, Tsai-Wen Wan, Hsu Wei-Yu, Xiang-Jun Chen, Hao-Chieh Chiu*, Yun-Tsung Huang*. Comparison of a Sepsityper® kit and in-house membrane filtration methods for rapidly diagnosing positive blood cultures via MALDI‒TOF MS. Journal of Microbiology Immunology and Infection. 2025 Apr;58: 265-271. [2023 IF=4.5; Infectious Diseases (23/132, Q1)]. 共同第一作者.

  2.    Tsai-Wen Wan, Yu-Tsung Huang, Jian-Hong Lai, Qiao-Ting Chao, Hui-Hui Yeo, and Tai-Fen Lee, Yung-Chi Chang, Hao-Chieh Chiu. The emergence of transposon-driven multidrug resistance in invasive nontypeable Haemophilus influenzae over the last decade. International Journal of Antimicrobial Agents. 2024 Oct;64(4):107319. [2023 IF=4.9; Infectious Diseases (16/132, Q1)]. 共同第一作者. 

  3.   Tai-Fen Lee,Tsai-Wen Wan, Hsu Wei-Yu, Xiang-Jun Chen, Hao-Chieh Chiu, Yun-Tsung Hunag. Comparison of a Sepsityper® kit and in-house membrane filtration methods for rapidly diagnosing positive blood cultures via MALDI‒TOF MS. Journal of Microbiology Immunology and Infection. 2024 Nov 30:S1684-1182(24)00213-5. [2023 IF=4.5; Infectious Diseases (23/132, Q1)]. 共同第一作者. 

  4.     Tsai-Wen Wan, Tai-Fen Lee, Xiang-Jun Chen, Yun-Tsung Hunag, Lee-Jene Teng, Po-Ren Hsueh, Hao-Chieh Chiu. Performance assessment of the Bruker Biotyper MALDI-TOF MS for the identification of difficult-to-identify viridans group streptococci. Journal of Clinical Microbiology. 2023 Dec 1:e0114323. [2022 IF=9.4; Microbiology (17/135, Q1)]. 共同第一作者. 

  5.     Xiang-Jun Chen, Tsai-Wen Wan, Qiuo-Ting Chao, Lee-Jene Teng, Tai-Fen Lee, Yu-Tsung Huang, Po-Ren Hsueh. Applicability of an in-house extraction protocol in a Bruker Biotyper matrix-assisted laser desorption/ionization time-of-flight mass spectrometry system for the identification of Streptococcus agalactiae from broth-enriched vaginal/rectal swab specimens. Journal of Microbiology Immunology and Infection. 2023 Aug;56(4):815-821. [2022 IF=7.4; Infectious Diseases (16/96, Q1)]. 第二作者. 

  6.  Tsai-Wen Wan, Hui-Hui Yeo, Tai-Fen Lee, Yu-Tsung Huang, Po-Ren Hsueh, Hao-Chieh Chiu. Molecular epidemiology of bacteraemic vancomycin-resistant Enterococcus faecium isolates and in vitro activities of SC5005 and other comparators against these isolates collected from a medical centre in northern Taiwan, 2019-2020. Journal of Antimicrobial Chemotherapy. 2023 Feb 1;78(2):457-465. [2022 IF=5.2; Microbiology (38/135, Q2)]. 第一作者. 

  7.    Shih-Hsiu Chou, Tsai-Wen Wan, Chung-Wai Shiau, Ling-Han Chen, Hsueh-Chun Lin, Hao-Chieh Chiu. Repurposing the tyrosine kinase inhibitor nilotinib for use against intracellular multidrug-resistant Salmonella Typhimurium. Journal of Microbiology Immunology and Infection. 2023 Jan 17;56(3):490-498. [2022 IF=7.4; Infectious Diseases (16/96, Q1)]. 共同第一作者. 

  8.     Hui-Hui Yeo, Chung-Wei Shiau, Yu-Hsuan Jao, Tsai-Wen Wan, Hao-Chieh Chiu. Rapid bactericidal activity of SC5005 combined with docosahexaenoic acid against multidrug-resistant Staphylococcus aureuspersisters and biofilms. Antimicrobial Agents and Chemotherapy. 2022 Dec 20;66(12):e0080322. [2021 IF=5.938; Pharmacology & Pharmacy (51/279, Q1)]. 第四作者. 

  9.  Tsai-Wen Wan, Hiromitsu Mori, Wei-Chun Hung, Lee-Jene Teng, Tatsuo Yamamoto. The phenomenon of staphylococcal interbacterial aggregate and net structures (SIAN) in community-associated methicillin-resistant Staphylococcus aureus CA-MRSA/J. Journal of Infection and Chemotherapy. 2022Nov;28(11):1584-1589. [2021 IF=2.065; Pharmacology & Pharmacy (229/279, Q4)]. 第一作者. 

  10.   Tsai-Wen Wan, Yu-Jung Liu, Yu-Ting Wang, Yu-Tzu Lin, Jia-Chuan Hsu, Jui-Chang Tsai, Hao-Chieh Chiu, Po-Ren Hsueh, Wei-Chun Hung, Lee-Jene Teng. Potentially conjugative plasmids harboring Tn6636, a multidrug-resistant and composite mobile element, in Staphylococcus aureus. Journal of Microbiology Immunology and Infection. 2022 Apr;55(2):225-233. [2021 IF=10.273; Infectious Diseases (15/95, Q1)]. 第一作者.代表著作

  11.   Yu-Tzu Lin, Wei-Chun Hung, Tsai-Wen Wan, Hsin Li, Tai-Fen Lee, Po-Ren Hsueh, Lee-Jene Teng. Staphylococcus taiwanensis sp. nov., isolated from human blood. International Journal of Systematic and Evolutionary Microbiology. 2022 Feb;72(2):005262. [2021 IF=2.689; Microbiology (106/137, Q4)].第三作者. 

• 12.  Tsai-Wen Wan, Lee-Jene Teng, Tatsuo Yamamoto.Unique surface structures of community-associated methicillin-resistant Staphylococcus aureus ST8/SCCmecIVl. Journal of Microbiology Immunology and Infection. 2021 Jun;54(3):527-530. [2020 IF=4.399; Infectious Diseases (27/93, Q2)]. 第一作者. 

  13.   Jia-Chuan Hsu, Tsai-Wen Wan, Hao Lee, Xiao-Mei Wang, Yu-Tzu Lin, Chiau-Jing Jung, Tai-Fen Lee, Po-Ren Hsueh, Lee-Jene Teng. Heterogeneity of molecular characteristics among Staphylococcus argenteus clinical isolates (ST2250, ST2793, ST1223, and ST2198) in northern Taiwan. Microorganisms 2020 Jul 30;8(8):1157. [2019 IF=4.152; Microbiology (37/136, Q2)]. 共同第一作者. 

  14.  Yu-Ting Wang, Yu-Tzu Lin, Tsai-Wen Wan, Der-Yuan Wang, Hsu-Yang Lin, Che-Yang Lin, Yu-Chih Chen, Lee Jene Teng. Distribution of antibiotic resistance genes among Staphylococcus species isolated from ready-to-eat foods. Journal of Food and Drug Analysis. 2019 Oct; 27(4), 841-848. [2018 IF=4.176; Food science & Technology (13/135, Q1)].第三作者. 

  15.   Tsai-Wen Wan, Lee Jene Teng, Tatsuo Yamamoto. Structures of a highly variable cell wall anchored protein encoding the spj gene from ST8/SCCmecIVl community associated methicillin resistant Staphylococcus aureus (CA MRSA/J) isolated from 2003 onwards: An indicator of a strongly invasive pathotype. Microbiology and Immunology. 2019 May; 63(5), 186-193. [2018 IF=1.442; Microbiology (116/133, Q4)]. 第一作者. 

  16.   Ishitobi N, Tsai-Wen Wan, Olga E. Khokhlova, Lee‐Jene Teng, Yamamori Y, Tatsuo Yamamoto. Fatal case of ST8/SCCmecIVl community-associated methicillin-resistant Staphylococcus aureus infection in Japan. New Microbes and New Infections. 2018 Aug; 26, 30-36. [2023 IF=2.9; Microbiology (58/132, Q2)]. 共同第一作者. 

  17.   Tsai-Wen Wan, Wataru Higuchi, Olga E. Khokhlova, Wei-Chun Hung, Yasuhisa Iwao, Masataka Wakayama, Noriyoshi Inomata, Tomomi Takano, Yu-Tzu Lin, Olga V. Peryanova, Kenji K. Kojima, Alla B. Salmina, Lee-Jene Teng, Tatsuo Yamamoto. Genomic comparison between Staphylococcus aureus GN strains clinically isolated from a familial infection case: IS1272 transposition through a novel inverted repeat-replacing mechanism. PLoS One. 2017; 12(11), e0187288. [2016 IF=2.806; Multidisciplinary sciences (15/64, Q1)]. 第一作者. 

  18.  Irina N. Protasova, Tsai-Wen Wan, Natalya V. Bakhareva, Wei‐Chun Hung, Wataru Higuchi, Yasuhisa Iwao, Tatyana A. Yelistratova, Natalya A. Ilyenkova, Yelena S. Sokolovskaya, Galina P. Martynova, Ivan V. Reva, Galina V. Reva, Sergey V. Sidorenko, Lee‐Jene Teng, Olga V. Peryanova, Alla B. Salmina, Tatsuo Yamamoto. Molecular characterization of Streptococcus pneumoniae, particularly serotype19A/ST320, which emerged in Krasnoyarsk, Russia. Microbiology and Immunology. 2017; 61(9), 359-370. [2016 IF=1.706; Microbiology (90/125, Q3)]. 共同第一作者. 

  19.   Tsai-Wen Wan, Wei-Chun Hung, Jui-Chang Tsai, Yu-Tzu Lin, Hao Lee, Po-Ren Hsueh, Tai-Fen Lee, Lee-Jene Teng. Novel structure of Enterococcus faecium-originated ermB-positive Tn1546-like element in Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. 2016; 60(10), 6108-6114. [2015 IF=4.415; Pharmacology & Pharmacy (34/255, Q1)]. 第一作者.

  20.   Tsai-Wen Wan, Olga E. Khokhlova, Yasuhisa Iwao, Wataru Higuchi, Wei-Chun Hung, Ivan V. Reva, Olga A. Singur, Vladimir V. Gostev, Sergey V. Sidorenko, Olga V. Peryanova, Alla B. Salmina, Galina V. Reva, Lee-Jene Teng, Tatsuo Yamamoto. Complete Circular Genome Sequence of successful ST8/SCCmec IV community-associated methicillin-resistant Staphylococcus aureus (OC8) in Russia: one- megabase genomic inversion, IS256's spread, and evolution of Russia ST8-IV. PLoS One. 2016; 11(10), e0164168.[2015 IF=3.057; Multidisciplinary sciences (11/63, Q1)]. 第一作者.

  21.   Wei-Chun Hung, Tsai-Wen Wan, Yu-Chia Kuo, Tatsuo Yamamoto, Jui-Chang Tsai, Yu-Tzu Lin, Po-Ren Hsueh, Lee-Jene Teng. Molecular evolutionary pathways toward two successful community-associated but multidrug-resistant ST59 methicillin-resistant Staphylococcus aureus lineages in Taiwan: dynamic modes of mobile genetic element salvages. PLoS One. 2016; 11(9), e0162526. [2015 IF=3.057; Multidisciplinary sciences (11/63, Q1)]. 第二作者.

  22.   Tsai-Wen Wan, Yusuke Tomita, Naoki Saita, Kanji Konno, Yasuhisa Iwao, Wei-Chun Hung, Lee-Jene Teng, T. Yamamoto. Emerging ST121/agr4 community-associated methicillin-resistant Staphylococcus aureus (MRSA) with strong adhesin and cytolytic activities: trigger for MRSA pneumonia and fatal aspiration pneumonia in an influenza-infected elderly. New Microbes and New Infections. 2016; 13, 17-21. [2023 IF=2.9; Microbiology (58/132, Q2)]. 共同第一作者.

  23.  Olga E. Khokhlova, Wei-Chun Hung, Tsai-Wen Wan, Yasuhisa Iwao, Tomomi Takano, Wataru Higuchi, Svetlana V. Yachenko,  Olga V. Teplyakova, Vera V. Kamshilova, Yuri V. Kotlovsky, Akihito Nishiyama, Ivan V. Reva, Sergey V. Sidorenko, Olga V. Peryanova, Galina V. Reva, Lee-Jene Teng, Alla B. Salmina, Tatsuo Yamamoto. Healthcare-and community-associated methicillin-resistant Staphylococcus aureus (MRSA) and fatal pneumonia with pediatric deaths in Krasnoyarsk, Siberian Russia: unique MRSA's multiple virulence factors, genome, and stepwise evolution. PLoS One. 2015; 10(6), e0128017. [2014 IF=3.234; Multidisciplinary sciences (9/57, Q1)]. 第三作者.