Education

1985~1991 PhD. Graduate Institute of Medicine, Kaohsiung Medical University,Kaohsiung, Taiwan

Profession Experiences

• 1992~ Associate professor, Department of Microbiology, Kaohsiung Medical University, Kaohsiung, Taiwan
• 2003~ Chief of Department of Microbiology, Kaohsiung Medical University, Kaohsiung, Taiwan
• 2012~ professor, Department of Microbiology, Kaohsiung Medical University, Kaohsiung, Taiwan

Research Interests

1. Pathogenesis of Helicobacter pylori
2. Molecular mechanism of neuropathic pain

Award

2008 & 2010 Best teaching tutor of KMU

Publications (2006~

• Wei-Chi Hsu, Yi-Chen Lee , Peir-In Liang , Lin-Li Chang, A-Mei Huang , Hui-Hui Lin , Wen-Jeng Wu , Ching-Chia Li , Wei-Ming Li , Jhen-Hao Jhan, Hung-Lung Ke*. CSF-1 Over-expression Predicts Poor Prognosis in upper tract urothelial carcinomas. Disease Markers. 2019,2724948. 2019,1-9.   I.F 2.761
• Hsueh-Ling Chang, Hung-Chen Wang, Yi-Ta Chunag, Chao-Wen Chou, I-Ling Lin, Chung-Sheng Lai, Lin-Li Chang & Kuang-I Cheng*. miRNA Expression Change in Dorsal Root Ganglia After Peripheral Nerve Injury. J Mol Neurosci. 2017,61(1):169-177. I.F 2.229.
• Chang LL, Hsu WH, Kao MC, Chou CC, Lin CC, Liu CJ, Weng BC, Kuo FC, Kuo CH, Lin MH, Wang CJ, Lin CH, Wu DC, Huang SK. Stromal C-type lectin receptor COLEC12 integrates H. pylori, PGE2-EP2/4 axis and innate immunity in gastric diseases. Scientific reports. 2018, 8(1):3821. I.F 4.259.
• Tseng KY, Wang HC, Chang LL, Cheng KI. Advances in Experimental Medicine and Biology: Intrafascicular Local Anesthetic Injection Damages Peripheral Nerve-Induced Neuropathic Pain. Adv Exp Med Biol. 2018, 2018:1099,65-76. I.F 1.76..
• Wang HC, Cheng KI, Chen PR, Tseng KY, Kwan AL, Chang LL. Glycine receptors expression in rat spinal cord and dorsal root ganglion in prostaglandin E2 intrathecal injection models. BMC Neuroscience. 2018,19(1):72. I.F 2.173.
• Chang CY, Lin HJ, Chang LL, Ma L, Siu LK, Tung YC, Lu PL* Characterization of Extended-Spectrum β-Lactamase-Carrying Plasmids in Clinical Isolates of Klebsiella pneumoniae from Taiwan. MICROBIAL DRUG RESISTANCE. 2017,23(1):98-106. I.F 2.306.
• Lee YC, Wu WJ, Lin HH, Li WM, Huang CN, Hsu WC, Chang LL, Li CC, Yeh HC, Li CF, Ke HL*.Prognostic Value of Leptin Receptor Overexpression in Upper Tract Urothelial Carcinomas in Taiwan. Clinical Genitourinary Cancer. 2017,15(4): e653-e659.   I.F 2.535.
• Hung-Lung Ke, Wei-Ming Li, Hui-Hui Lin, Wei-Chi Hsu, Ya-Ling Hsu, Lin-Li Chang,,Chun-Nung Huang, Ching-Chia Li, Hsin-Ping Chang, Hsin-Chih Yeh, Chien-Feng Li,Wen-Jeng Wu . Hypoxia-regulated MicroRNA-210 Overexpression is Associated with Tumor Development and Progression in Upper Tract Urothelial Carcinoma International Journal of Medical Sciences. 2017,14(6):578-584. I.F 2.399.
• Wei-Ming Li, Chun-Nung Huang, Yi-Chen Lee, Szu-Han Chen, Hui-Hui Lin, Wen-JengWu, Ching-Chia Li, Hsin-Chih Yeh, Lin-Li Chang, Wei-Chi Hsu, Hung-Lung Ke.       Over-expression of Activated Signal Transducer and Activator of Transcription 3 Predicts Poor Prognosis in Upper Tract Urothelial Carcinoma. International Journal of Medical Sciences. 2017,14(13):1360-1367. I.F 2.399.
• Cheng Kuang-I , Wang Hung-Chen , Wu Yi-Chia ,Tseng Kuang-Yi , Chuang Yi-Ta, Chou Chao-Wen, Chen Ping-Luen, Chang Lin-Li ,Lai Chung-Sheng. Sciatic Nerve Intra-fascicular Lidocaine Injection-Induced Peripheral Neuropathic Pain: Alleviation by Systemic Minocycline Administration. CLINICAL JOURNAL OF PAIN. 2016, 32(6):513–521. I.F 2.712.
• Cheng YC, Huang CN, Wu WJ, Li CC, Ke HL, Li WM, Tu HP, Li CF, Chang LL, Yeh HC*. The prognostic significance of inflammation-associated blood cell markers in patients with upper tract urothelial carcinoma. ANNALS OF SURGICAL ONCOLOGY .2016,23(1):343-351.    I.F 3.655.
• Yeh HC, Huang CN, Li CC, Chang LL, Lin HH, Ke HL, Huang AM, Liang PI, Li CF, Wu WJ*. Overexpression of PTP4A3 is associated with metastasis and unfavorable prognosis in bladder cancer . WORLD JOURNAL OF UROLOGY. 2016, 34(6):835-846. I.F 2.397.
• LI WN, WEI YC, HUANG CN, KE HL, LI CC, YEH HC, CHANG LL, HUANG CH, LI CF*, WU WJ*. Matrix Metalloproteinase-11 as a Marker of Metastasis and Predictor of Poor Survival in Urothelial Carcinomas. JOURNAL OF SURGICAL ONCOLOGY. 2016, 113(6):700-707.  I.F 3.151.
• Kuo CH, Liu CJ, Yang CC, Kuo FC, Hu HM, Shih HY, Wu MC, Chen YH, Wang HM, Ren JL, Wu DC, Chang LL . A Rapid and Accurate Method to Evaluate Helicobacter pylori Infection, Clarithromycin Resistance, and CYP2C19 Genotypes Simultaneously From Gastric Juice. MEDICINE. 2016,95(21):e3458. I.F 2.133.
• Wang HC, Cheng KI, Chou CW, Kwan AL*, Chang LL*.  Intrathecal CGS26303 Pre-treatment Attenuates Spinal Nerve Ligation-Induced Neuropathic Pain in the Spinal Cord. World Neurosurgery. 2016,91:532-541. I.F 2.685.
• Li WM, Huang CN, Ke HL, Li CC, Wei YC, Yeh HC, Chang LL, Huang CH, Liang PI, Yeh BW, Chan TC, Li CF*, Wu WJ*. MCM10 overexpression implicates adverse prognosis in urothelial carcinoma.  Oncotarget.2016,7(47):77777-77792. I.F 5.008.
• Lin JN, Chang LL, Lai CH, Lin KJ, Lin MF, Yang CH, Lin HH, Chen YH.   Development of an animal model for alcoholic liver disease in zebrafish. Zebrafish. 2015,12(4):271-280. I.F 1.946.
• Lin JN, Chang LL, Lai CH, Huang YH, Chen WF, Yang CH, Hsu J, Lin HH, Chen YH. High prevalence of fluoroquinolone-nonsusceptible Streptococcus pyogenes emm12 in Taiwan. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE. 2015,83(2):187-192.   I.F 2.457.
• Hung-Lung KE , Hui-Hui Lin, Wei-Ming Li,Ching-Chia Li, Lin-Li Chang , Yi-Chen Lee, Chun-Nung Huang, Wen-Jeng Wu. High visfatin expression predicts poor prognosis of upper tract urothelial carcinoma patients. American Journal of Cancer Research.2015,5(8):2447-2454. I.F 4.165.
• Yeh HC, Li CC, Huang CN, Hour TC, Yeh BW, Li WM, Liang PI, Chang LL, Li CF, Wu WJ  .PTP4A3 independently predicts metastasis and survival in upper tract urothelial carcinoma treated with radical nephroureterectomy. JOURNAL OF UROLOGY. 2015,194(5):  1449-1455  .I.F 4.36.
• Chung-Hsu Lai, Lin-Li Chang, Jiun-Nong Lin, Ming-Huei Liao, Shyh-Shyan Liu, Hsu-Hsun Lee, Hsi-Hsun Lin, Yen-Hsu Chen. Association of Human Q Fever with Animal Husbandry, Taiwan, 2004–2012. EMERGING INFECTIOUS DISEASES. 2015,21(12):2217-2220. I.F 6.751.
• K.-I. Cheng, H.-C. Wang, Y.-T. Chuang, C.-W. Chou, H.-P. Tu, Y.-C. Yu, L.-L. Chang,*, C.-S. Lai*. Persistent mechanical allodynia positively correlates with an increase in activated microglia and increased P-p38 mitogen-activated protein kinase activation in streptozotocin-induced diabetic rats. EUROPEAN JOURNAL OF PAIN.2014,18(2):162-173..I.F.3.218.
• Kuo CH, Lu CY, Yang YC, Chin C, Weng BC, Liu CJ, Chen YH, Chang LL, Kuo FC, Wu DC*, Su HL. Does Long-Term Use of Silver Nanoparticles Have Persistent Inhibitory Effect on H. pylori Based on Mongolian Gerbil’s Model.Biomed Research International.2014,461034(1-7) .I.F 1.579.
• Lai CH, Chang LL, Lin JN, Tsai KH, Hung YC, Kuo LL, Lin HH, Chen YH.  Human Spotted Fever Group Rickettsioses Are Underappreciated in Southern Taiwan, Particularly for the Species Closely-Related to Rickettsia felis. PLoS ONE.2014,9.4.e95810(1-9).  I.F 3.534.
• Kuo CH, Chen YH, Goh KL, Chang LL.Helicobacter pylori and Systemic Disease Gastroenterology Research and Practice.2014 ,2014-358494(1-3).I.F 1.502.
• Lai CH, Chang LL, Lin JN, Chen WF, Wei YF, Chiu CT, Wu JT, Hsu CK, Chen JY, Lee HS, Lin HH, Chen YH. Clinical characteristics of q Fever and etiology of community-acquired pneumonia in a tropical region of southern taiwan: a prospective observational study. PLoS One 2014,9.7.e102808(1-11). I.F 3.534.
• Chung-Hsu Lai, Jiun-Nong Lin, Yen-Hsu Chen, Lin-Li Chang, Wen-Ying Huang, Hsiao-Pei Ku, Hsi-Hsun Lin* .The first imported human case of Yersinia pseudotuberculosis serotype O1 septicemia presents with acute appendicitis-like syndrome in Taiwan. Journal of the Formosan Medical Association. 2014.113(9):656–659. I.F 1.695.
• Lin JN1, Chang LL, Lai CH, Lin HH, Chen YH*.Association between polymorphisms in the csrRS two-component regulatory system and invasive group A streptococcal infection . EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES 2014, 33(5):735-743. I.F 2.544.
• Cheng KI, Lin IL, Chang LL*, Jou IM, Lai CS, Wang JJ, Wang HC, Kwan AL*    Application of quinidine on rat sciatic nerve decreases the amplitude and increases the latency of evoked responses. Journal of Anesthesia. 2014,28(4):559-568. I.F 1.117.
• Cheng KI, Wang HC, Chuang YT, Chou CW, Tu HP, Yu YC, Chang LL, Lai CS. Persistent mechanical allodynia positively correlates with an increase in activated microglia and increased P-p38 mitogen-activated protein kinase activation in streptozotocin-induced diabetic rats. Eur J Pain. 2014, 18:162-173. doi: 10.1002/j.1532-2149.2013.00356.x. [Epub ahead of print] (correspondence author)
• Kuang-I Cheng, I-Ling Lin, Lin-Li Chang, I-Ming Jou, Chung-Sheng Lai, Jhi-Joung Wang, Hung-Chen Wang, Aij-Lie Kwan Application of quinidine on rat sciatic nerve decreases the amplitude and increases the latency of evoked responses. Journal of Anesthesia. 2014, DOI 10.1007/s00540-014-1808-8 (correspondence author)
• Lin JN, Chang LL, Lai CH, Lin HH, Chen YH. Association between polymorphisms in the csrRS two-component regulatory system and invasive group A streptococcal infection. Eur J Clin Microbiol Infect Dis 2013 DOI 10.1007/s10096-013-2005-7.
• Chao-Hung Kuo, Sophie S. W. Wang, Chien-Yu Lu, Huang-Ming Hu, Fu-Chen Kuo, Bi-ChuangWeng, Chun-Chieh Wu, Chung-Jung Liu, Pei-Yun Tsai, Tsung-Cheng Lee, Li-Wei Chen, Kuang-Hung Cheng, Lin-Li Chang, Deng-Chyang Wu. Long-Term Use of probiotic-Containing Yogurts Is a Safe Way to Prevent Helicobacter pylori: Based on a Mongolian Gerbil’s Model. Biochemistry Research International. 2013, 594561.
• Jiun-Nong Lin, Lin-Li Chang, Chung-Hsu Lai, Hsi-Hsun Lin, Yen-Hsu Chen. Emergence of Streptococcus pyogenes emm102 Causing Toxic Shock Syndrome in Southern Taiwan during 2005–2012. PLoS ONE 8(12): e81700. doi:10.1371/journal.pone.0081700.
• Chung-Hsu Lai, Lin-Li Chang, Jiun-Nong Lin, Wei-Fang Chen, Li-Li Kuo, Hsi-Hsun Lin, Yen-Hsu Chen. High Seroprevalence of Mycoplasma pneumoniae IgM in Acute Q Fever by Enzyme-Linked Immunosorbent Assay (ELISA). PLoS ONE 2013, 8:
• Lin JN, Chang LL, Lai CH, Lin HH, Chen YH. Group A Streptococcal Necrotizing Fasciitis in the Emergency Department. J Emerg Med. 2013 Aug 9. pii: S0736-4679(13)00578-7. doi: 10.1016/j.jemermed.2013.05.046. [Epub ahead of print
• Lin JN, Chang LL, Lai CH, Lin HH, Chen YH. Trivial trauma, lethal outcome: streptococcal toxic shock syndrome presenting to the ED. Am J Emerg Med. 2013 Aug;31(8):1293
• Lee YC, Wu WJ, Li WM, Lin HH, Huang CN, Chai CY, Chang LL, Lin HL, Ke HL. Prognostic value of p53 protein overexpression in upper tract urothelial carcinomas in Taiwan. Anticancer Res. 2013 Mar;33(3):1091-8
• Yao-Kang HUANG, Meng-Chieh WU, Sophie SW WANG, Chao-Hung KUO, Yi-Chern LEE, Ling-Li CHANG, Tsung-Hsi WANG, Yen-Hsu CHEN, Wen-Ming WANG, Deng-Chyang WU, Fu-Chen KUO. Lansoprazole-based sequential and concomitant therapy for the first-line Helicobacter pylori eradication. Journal of Digestive Diseases 2012; 13; 232–238
• Ke HL, Tu HP, Lin HH, Chai CY, Chang LL, Li WM, Li CC, Lee YC, Yeh HC, Wu WJ, Bau DT. Cyclooxygenase-2 (COX-2) up-regulation is a prognostic marker for poor clinical outcome of upper tract urothelial cancer. Anticancer Res. 2012 Sep;32(9):4111-6
• Cheng KI, Wang HC, Chang LL, Wang FY, Lai CS, Chou CW, Tsai HP, Kwan AL. Pretreatment with intrathecal amitriptyline potentiates anti-hyperalgesic effects of post-injury intra-peritoneal amitriptyline following spinal nerve ligation. BMC Neurol. 2012 Jun 1;12(1):44. (correspondence author)
• Chang LL, Wang SW, Wu IC, Yu FJ, Su YC, Chen YP, Wu DC, Kuo CH, Hung CH. Impaired dendritic cell maturation and IL-10 production following H. pylori stimulation in gastric cancer patients. Appl Microbiol Biotechnol. 2012 Apr 13. [Epub ahead of print]
• Lin HH, Ke HL, Wu WJ, Lee YH, Chang LL*. Hypermethylation of E-cadherin, p16, p14, and RASSF1A genes in pathologically normal urothelium predict bladder recurrence of bladder cancer after transurethral resection. Urol Oncol. 2012, 30(2): 177-81. (correspondence author)
• Lin JN, Chen YH, Chang LL, Lai CH, Lin HL, Lin HH. Clinical characteristics and outcomes of patients with extended-spectrum β-lactamase-producing bacteremias in the emergency department. Intern Emerg Med. 2011 Dec;6(6):547-55.
• Lin JN, Chang LL, Lai CH, Lin HH, Chen YH. Clinical and Molecular Characteristics of Invasive and Noninvasive Skin and Soft-Tissue Infections Caused by Group A Streptococcus. J Clin Microbiol. 2011, 49(10): 3632-7.
• Lin HH, Ke HL, Hsiao KH, Tsai CW, Wu WJ, Bau DT, Chang LL. Potential role of CCND1 G870A genotype as a predictor for urothelial carcinoma susceptibility and muscle-invasiveness in Taiwan. Chin J Physiol. 2011 Jun 30;54(3):196-202 (correspondence author)
• Cheng KI, Wang HC, Lai CS, Tsai HP, Kwan AL, Ho ST, Wang JJ, Chang LL. Pre-emptive intrathecal quinidine alleviates spinal nerve ligation-induced peripheral neuropathic pain. J Pharm Pharmacol. 2011 Aug;63(8):1063-9. (correspondence author)
• Cheng KI, Lai CS, Wang FY, Wang HC, Chang LL, Ho ST, Tsai HP, Kwan AL. Intrathecal lidocaine pretreatment attenuates immediate neuropathic pain by modulating Nav1.3 expression and decreasing spinal microglial activation. BMC Neurol. 2011 Jun 16;11:71 (correspondence author)
• Lin HH, Ke HL, Hsiao KH, Tsai CW, Wu WJ, Bau DT, Chang LL. CCND1 1722 polymorphism and potential relevance to upper tract urothelial cancer. Anticancer Res. 2011 Mar;31(3):1043-7 (correspondence author)
• Chang CY, Lu PL, Lin CC, Lee TM, Tsai MY, Chang LL*. Integron types, gene cassettes, antimicrobial resistance genes and plasmids of Shigella sonnei isolates from outbreaks and sporadic cases in Taiwan. J Med Microbiol. 2011, 60:197-204. (correspondence author)
• Ke HL, Chang LL, Yang SF, Lin HH, Li CC, Wu DC, Wu WJ. Osteopontin overexpression predicts poor prognosis of upper urinary tract urothelial carcinoma. Urol Oncol. 2011, 29(6):703-9.
• Cheng KI, Lin SR, Chang LL, Wang JY, Lai CS. Association of the functional A118G polymorphism of OPRM1 in diabetic patients with foot ulcer pain. J Diabetes Complications. 2010 Mar-Apr;24(2):102-8.
• Lin HH, Ke HL, Huang SP, Wu WJ, Chen YK, Chang LL. Increase sensitivity in detecting superficial, low grade bladder cancer by combination analysis of hypermethylation of E-cadherin, p16, p14, RASSF1A genes in urine. Urol Oncol. 2010-Dec;28(6):597-602. (correspondence author)
• Lin JN, Lai CH, Chen YH, Chang LL, Lee SS, Lin HH. Immune reconstitution inflammatory syndrome presenting as chylothorax in a patient with HIV and Mycobacterium tuberculosis coinfection: a case report. BMC Infect Dis. 2010 Nov 8;10:321.
• Lin JN, Lai CH, Chen YH, Chang LL, Lu PL, Tsai SS, Lin HL, Lin HH. Characteristics and outcomes of polymicrobial bloodstream infections in the emergency department: A matched case-control study. Acad Emerg Med. 2010 Oct;17(10):1072-9.
• Lai CH, Lin JN, Chang LL, Chen YH, Lin HH. Circulating cytokines and procalcitonin in acute Q fever granulomatous hepatitis with poor response to antibiotic and short-course steroid therapy: a case report. BMC Infect Dis. 2010 Jul 1;10:193.
• Chan HC, Ke LY, Liu CC, Chang LL, Tsai WC, Liu HW, Yen JH. Increased expression of suppressor of cytokine signaling 1 mRNA in patients with rheumatoid arthritis. Kaohsiung J Med Sci. 2010 Jun;26(6):290-8.
• Yeh HC, Huang CH, Yang SF, Li CC, Chang LL, Lin HH, Ke HL, Wei YC, Wu WJ. Nuclear factor-κB activation predicts an unfavourable outcome in human Upper urinary tract urothelial carcinoma. BJU Int. 2010 Oct;106(8):1223-9.
• Chan HC, Ke LY, Chang LL, Liu CC, Hung YH, Lin CH, Li RN, Tsai WC, Liu HW, Yen JH. Suppressor of cytokine signaling 1 gene expression and polymorphisms in systemic lupus erythematosus. Lupus. 2010 May;19(6):696-702.
• Lai CH, Chen YH, Lin JN, Chang LL, Chen WF, Lin HH. Acute Q fever and scrub typhus, southern Taiwan. Emerg Infect Dis. 2009 Oct;15(10):1659-61
• Lai CH, Huang CK, Chen YH, Chang LL, Weng HC, Lin JN, Chung HC, Liang SH, Lin HH. Epidemiology of acute q Fever, scrub typhus, and murine typhus, and identification of their clinical characteristics compared to patients with acute febrile illness in southern taiwan. J Formos Med Assoc. 2009 May;108(5):367-76.
• Tan LB, Chang LL, Cheng KI, Huang CH, Kwan AL. Transitional cell carcinomas of the renal pelvis and the ureter: comparative demographic characteristics, pathological grade and stage and 5-year survival in a Taiwanese population. BJU Int. 2009 Feb;103(3):312-6.
• Kuo CH, Hu HM, Tsai PY, Wu IC, Yang SF, Chang LL, Wang JY, Jan CM, Wang WM, Wu DC. Short-term celecoxib intervention is a safe and effective chemopreventive for gastric carcinogenesis based on a Mongolian gerbil model. World J Gastroenterol. 2009 Oct 21;15(39):4907-14
• Chang CY, Fang YT, Tsai SM, Chang LL, Yu WL. Characterization of class 1 integrons and gene cassettes in clinical isolates of Klebsiella pneumoniae from Taiwan. Diagn Microbiol Infect Dis. 2009 Oct;65(2):214-6
• Tseng YS, Wu DC, Chang CY, Kuo CH, Yang YC, Jan CM, Su YC, Kuo FC, Chang LL. Amoxicillin resistance with beta-lactamase production in Helicobacter pylori. Eur J Clin Invest. 2009 Sep;39(9):807-12. (correspondence author)
• Kuo CH, Hu HM, Kuo FC, Hsu PI, Chen A, Yu FJ, Tsai PY, Wu IC, Wang SW, Li CJ, Weng BC, Chang LL, Jan CM, Wang WM, Wu DC. Efficacy of levofloxacin-based rescue therapy for Helicobacter pylori infection after standard triple therapy: a randomized controlled trial. J Antimicrob Chemother. 2009 May;63(5):1017-24.
• Chang KP, Lai CH, Huang SH, Tai HT, Chang LL, Lin SD, Hwang SL, Lai CS. Downregulation of Janus kinase 3 expression by small interfering RNA in rat composite tissue allotransplantation. Transpl Immunol. 2009 May;21(1):27-32.
• Lee YC, Lin HH, Wang CJ, Liu CC, Wu WJ, Huang CH, Chang LL. The associations among GNB3 C825T polymorphism, erectile dysfunction, and related risk factors. J Sex Med. 2008 Sep;5(9):2061-8. (correspondence author)
• Kuo CH, Hu HM, Tsai PY, Yang SF, Chang LL, Wang JY, Chen A, Jan CM, Wang WM, Wu DC. A better method for confirming Helicobacter pylori infection in Mongolian gerbils. J Gastroenterol. 2008;43(1):32-7.
• Chang KP, Huang SH, Lin CL, Chang LL, Lin SD, Lai CS. An alternative model Of composite tissue allotransplantation: groin-thigh flap. Transpl Int. 2008 Jun;21(6):564-71.
• Chang LL, Lin HH, Chang CY, Lu PL. Increased incidence of class 1 integrons in trimethoprim/sulfamethxazole- resistant clinical isolates of Stenotrophomonas maltophilia. J Antimicrob Chemother. 2007 59(5):1038-9.
• Chang TM, Lu PL, Li HH, Chang CY, Chen TC, Chang LL. Characterization of fluoroquinolone resistance mechanisms and their correlation with the degree of resistance to clinically used fluoroquinolones among Escherichia coli isolates. J Chemother. 2007 Oct;19(5):488-94. (correspondence author)
• Kuo CH, Yu FJ, Tsai PY, Yang SF, Chang LL, Jan CM, Wang WM, Wu DC. Evaluating the validity of the serologic test for detecting Helicobacter pylori infection in Mongolian gerbils. Kaohsiung J Med Sci. 2007 Nov;23(11):545-51.
• Lee YC, Huang CH, Wang CJ, Liu CC, Wu WJ, Chang LL, Lin HH. The associations among eNOS G894T gene polymorphism, erectile dysfunction andrelated risk factors. BJU Int. 2007 Nov;100(5):1116-20.
• Chang LL, Chang TM, Chang CY. Variable gene cassette patterns of class 1 integron-associated drug-resistant Escherichia coli in Taiwan. Kaohsiung J Med Sci. 2007 Jun;23(6):273-80.
• Lu CY, Kuo FC, Wang SW, Lo YC, Wu IC, Chang LL, Yu FJ, Su YC, Wang WM, Jan CM, Wu DC. The clinical applications and accuracy of 2 rapid near-patientTests in detecting Helicobacter pylori infection. Diagn Microbiol Infect Dis. 2006 Nov;56(3):241-6.
• Wu IC, Wang SW, Yang YC, Yu FJ, Kuo CH, Chuang CH, Lee YC, Ke HL, Kuo FC, Chang LL, Wang WM, Jan CM, Wu DC. Comparison of a new office-based Stool immunoassay and (13)C-UBT in the diagnosis of current Helicobacter pylori infection. J Lab Clin Med. 2006 Mar;147(3):145-9.